Drug interaction inconsistency in Drug Information Handbook
نویسندگان
چکیده
منابع مشابه
The Prevalence of Drug-Drug Interaction and Inappropriate Drug Prescription Among the Elderly in Kashan
Background: Drug-drug Interaction (DDI) among the elderly is one of the major healthcare challenges worldwide. The present study assessed the rates of DDI and inappropriate drug prescription among the elderly in Kashan City, Iran. Methods: This descriptive-analytical study was designed, conducted, and reported according to the guideline of Strengthening the Reporting of Observational Studies ...
متن کاملEvaluating drug-drug interaction information in NDF-RT and DrugBank
BACKGROUND There is limited consensus among drug information sources on what constitutes drug-drug interactions (DDIs). We investigate DDI information in two publicly available sources, NDF-RT and DrugBank. METHODS We acquire drug-drug interactions from NDF-RT and DrugBank, and normalize the drugs to RxNorm. We compare interactions between NDF-RT and DrugBank and evaluate both sources against...
متن کاملcomparative dna interaction studies of antiviral drug, zidovudine and its complex using different instrumental methods
هدف از این مطالعه بررسی امکان استفاده از داروهای شناخته شده در درمان سایر بیماریها به عنوان داروهای ضد سرطان است. همچنین با استفاده از این داروها در ساختمان کمپلکس فلز می توان شاخص های دارویی بدست آمده را بررسی نمود. داروی ضد ویروس ایدز(hiv)به نام زیدوودین(azt)انتخاب و.کمپلکس.محلول.در.آب[pt(azt)2]cl2سنتزو به روشهای مختلف فیزیکی و شیمیایی شناسایی گردید. بر هم کنش مقایسه ای این دارو و کمپلکس پلا...
15 صفحه اولDrug-drug interaction prediction assessment.
Model-based drug-drug interaction (DDI) is an important in-silico tool to assess the in vivo consequences of in vitro DDI. Before its general application to new drug compounds, the DDI model is always established from known interaction data. For the first time, tests for difference and equivalent tests are implemented to compare reported and model-base simulated DDI (log AUCR) in the sample mea...
متن کاملDrug-Drug Interaction Pattern Recognition
BACKGROUND AND OBJECTIVE Drug-drug interaction (DDI) is an important aspect of drug development, especially for safety. When a drug is used concomitantly with other drug(s), one of the major concerns is the change of exposures, including the rate and extent of drug absorption, distribution, metabolism and elimination. To address the concerns, a common practice is to measure and report the diffe...
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ژورنال
عنوان ژورنال: American Journal of Health-System Pharmacy
سال: 1998
ISSN: 1079-2082,1535-2900
DOI: 10.1093/ajhp/55.22.2418